New study examined a diet with calorie restriction two days per week was comparable to a diet with daily calorie restriction for glycemic control in patients with type 2 diabetes.
‘Effect of twice-weekly calorie restriction diet for glycemic control in patients with type 2 diabetes was analyzed.’
What and When: 137 patients with type 2 diabetes were assigned to 1 of 2 diets between April 2015 and September 2017
What (Study Interventions and Outcomes): 70 patients assigned to an intermittent calorie restriction diet (500-600 calories/day) on two nonconsecutive days with their regular diet the other five days per week and 67 patients assigned to a daily calorie restriction diet (1,200-1,500 calories/day) for 12 months (interventions); change in hemoglobin A1c (primary outcome)
How (Study Design): This was a randomized noninferiority trial. This type of randomized clinical trial is designed to assess whether an intervention is “no worse” than the comparison intervention.
Authors: Peter M. Clifton, M.D., Ph.D., of the University of South Australia, Adelaide, and coauthors
Results: The average change in hemoglobin A1c after a year was comparable between the two diets.
Study Limitations: The study population had well-controlled type 2 diabetes; medication adjustments can complicate interpreting changes in hemoglobin A1c levels; and study participants had more contact with a dietitian than is usual in a clinical setting