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January 24, 2020

Zika Virus – A New Mosquito-Borne Disease in the West

The spread of Zika virus, an arbovirus or mosquito-borne
virus infection to the West has been highlighted in an article in the New England Journal of Medicine.

International travel and overcrowding are some
of the reasons that have resulted in the appearance of four mosquito-borne diseases
in the Western world in the last 20 years. After dengue, chikungunya and West Nile virus, the latest entrant is the Zika virus, with the first cases reported in
Brazil and Puerto Rico in May and December 2015, respectively.

‘Zika virus disease is a newly emerged mosquito-borne disease that has similar clinical signs to dengue, and may be misdiagnosed in areas where dengue is common.’

Several similarities have been observed between
zika virus and the other viral infections. It has been noted that Zika infections
occur in areas that have recently been plagued by chikungunya
infection. Like yellow fever,
dengue and chikungunya infections, Zika also
spreads through the bite of the Aedes aegypti
. The mosquito breeds in fresh stored water in homes, and bites during
the daytime.
usually causes a mild disease with symptoms similar to dengue
. Symptoms include fever, muscle aches, rash,
joint pains and conjunctivitis or sore eyes. However, several people with Zika have
suffered from a neurological problem called Guillain-Barré syndrome, which could possibly be a complication of Zika. There is also a concern
that, unlike the other viral infections, Zika may cause birth defects- in Brazil, several babies have been born with small heads since the appearance
of the infection last year.

of Zika is made on clinical basis, but it may be confused with dengue or chikungunya
due to similar symptoms
. The
reverse transcriptase polymerase chain reaction test may be used to differentiate
it from other viral infections. This test is however currently available only in
certain centers.

to other viral infections like dengue and chikungunya, treatment of Zika is currently
non-specific, with
bed rest and supportive care. Unlike dengue, Zika is not known to cause bleeding.
However, to be on the safe side, medications like aspirin have to be avoided till
dengue has been ruled out. A vaccine to prevent Zika is not available, and even
if developed, its clinical utility in vaccinating large populations will have to
be established.

Though currently there is no specific drug for
the treatment of Zika infection, experts feel that it would be more useful to develop
drugs that will be effective against
more than one viral infections, rather than trying to develop one drug against each
viral infection.

no specific treatment is available, prevention forms an important aspect in the
management of viral mosquito-borne diseases
. Prevention of Zika and other mosquito-borne viral infections involves preventing mosquito bites by using mosquito
screens, insect repellents and cleaning
up of mosquito-breeding sites. The last step may not always be possible in crowded
places with poor sanitation where, unfortunately, the infection is commonly noted.


Fauci AS and Morens DM. Zika Virus in the Americas — Yet Another Arbovirus Threat
January 13, 2016 DOI: 10.1056/NEJMp1600297


Source: Medindia

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